5G CELL PHONE EMF AND COVID, A PLAUSIBLE SYNERGISM INCREASING RISKS TO NEUROLOGICAL HEALTH VIA MITOCHONDRIAL OXIDATIVE AND DNA DAMAGE. 2022-11-14. Jorma Jyrkkanen

J Clin Transl Res. 2021 Oct 26; 7(5): 666–681. Published online 2021 Sep 29. PMCID: PMC8580522 PMID: 34778597 Evidence for a connection between coronavirus disease-19 and exposure to radiofrequency radiation from wireless communications including 5G Beverly Rubik 1 , 2 , * and Robert R. Brown 3 Abstract Background and Aim: Coronavirus disease (COVID-19) public health policy has focused on the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus and its effects on human health while environmental factors have been largely ignored. In considering the epidemiological triad (agent-host-environment) applicable to all disease, we investigated a possible environmental factor in the COVID-19 pandemic: ambient radiofrequency radiation from wireless communication systems including microwaves and millimeter waves. SARS-CoV-2, the virus that caused the COVID-19 pandemic, surfaced in Wuhan, China shortly after the implementation of city-wide (fifth generation [5G] of wireless communications radiation [WCR]), and rapidly spread globally, initially demonstrating a statistical correlation to international communities with recently established 5G networks. In this study, we examined the peer-reviewed scientific literature on the detrimental bioeffects of WCR and identified several mechanisms by which WCR may have contributed to the COVID-19 pandemic as a toxic environmental cofactor. By crossing boundaries between the disciplines of biophysics and pathophysiology, we present evidence that WCR may: (1) cause morphologic changes in erythrocytes including echinocyte and rouleaux formation that can contribute to hypercoagulation; (2) impair microcirculation and reduce erythrocyte and hemoglobin levels exacerbating hypoxia; (3) amplify immune system dysfunction, including immunosuppression, autoimmunity, and hyperinflammation; (4) increase cellular oxidative stress and the production of free radicals resulting in vascular injury and organ damage; (5) increase intracellular Ca2+ essential for viral entry, replication, and release, in addition to promoting pro-inflammatory pathways; and (6) worsen heart arrhythmias and cardiac disorders. Relevance for Patients: In short, WCR has become a ubiquitous environmental stressor that we propose may have contributed to adverse health outcomes of patients infected with SARS-CoV-2 and increased the severity of the COVID-19 pandemic. Therefore, we recommend that all people, particularly those suffering from SARS-CoV-2 infection, reduce their exposure to WCR as much as reasonably achievable until further research better clarifies the systemic health effects associated with chronic WCR exposure. Keywords: COVID-19, Coronavirus, coronavirus disease-19, severe acute respiratory syndrome, coronavirus 2, electromagnetic stress, electromagnetic fields, environmental factor, microwave, millimeter wave, pandemic, public health, radio frequency, radiofrequency, wireless SEE ALSO MY STUDY ON EMF AND CANCER, i FOUND CANCER OF THE BRAIN, LEUKEMIAS, DEFORMITIES AND MISCARRIAGES This is my conclusion from a massive literature review. INTRODUCTION This EMF Cancer review is based on literature references obtained from Bonneville Power, Battelle and BC Hydro, spanning 1979-1989 and from a computor search of DIALOG databases for 1989-90. I have since become aware that DIALOG has had a legal battle with CAS, Chemical Abstracts Society, and this may have led to less reporting of actual published research than that which I obtained at least for my 1989-90 computor online update, so there may be gaps. How the librarian chose which studies I would receive from the total list I asked for is not clear so a source of bias could have been enterred there. It has also been argued that findings which show no effects are less likely to get published. I seriously question this however, since it is in the vested interests of utilities to make widely known any such null effects, and they would promote the publication of such studies. If anything, perhaps the reverse is true. Perhaps these two tendencies cancel out and a truly representative pattern of negative and positive findings is in fact published. There is a massive problem with controls in the majority of these studies since EMF is so wide-spread, it is almost impossible to get an unexposed group. The best that can be hoped for is a less exposed group. However, even this runs into trouble interpretation-wise when one considers that specific windows of frequency and intensity and combinations may be more important in causality than simple density of electric or magnetic fields. The effect of using national averages as controls where even the controls have been exposed to EMF to some degree, is to underestimate the true effect of EMF so that5 it is safe to say that it is worse than experimentally demonstrated. RESULTS The conclusions one is drawn to from an overview such as this are inescapable. EMF or something to do with EMF makes leukemia worse if not actually causing it or some forms of it, though the evidence points strongly towards causality. Brain cancer is made worse or actually caused by EMF or an associated factor. Other cancers are probably made worse or promoted by EMF exposure. Fundamental genetic and perhaps epigenetic cellular physiology changes occur, some permanently, from certain tunings or windows of EMF. Effects on development can be profound and species variability in susceptability to EMF impacts is largely unknown. Confounding variables like chemical pollutants, solvent vapors, metals, may be operative synergistically as initiators, promoters, physiological poisons, hormone analogs, or cocarcinogens or may work through harming the immune system. CONCLUSION MITOCHONDRIAL OXIDATION DAMAGE INDUCED BY EMF Exposure to 900 MHz EMF has provided evidence of causation of blood-brain barrier damage, induction of glial reactivity, and initiation of biochemical modifications in the rat brain (17, 27). Xu et al. (28) determined that exposure to 1,800 MHz RF EMF promoted oxidative damage to mitochondrial DNA and changed the activity of neuron function. Dindic et al. (8) reported biochemical and histopathological changes after MP exposure on rat brain. REFERENCE: WU ET. AL. ABSTRACT FINDS MECHANISM FOR NEUROTOXICITY OF CELL PHONE FREQUENCIES we exposed primary cultured cortical neurons to pulsed RF electromagnetic fields at a frequency of 1800 MHz modulated by 217 Hz at an average special absorption rate (SAR) of 2 W/kg. At 24 h after exposure, we found that RF radiation induced a significant increase in the levels of 8-hydroxyguanine (8-OHdG), a common biomarker of DNA oxidative damage, in the mitochondria of neurons. Concomitant with this finding, the copy number of mtDNA and the levels of mitochondrial RNA (mtRNA) transcripts showed an obvious reduction after RF exposure. Each of these mtDNA disturbances could be reversed by pretreatment with melatonin, which is known to be an efficient antioxidant in the brain. Together, these results suggested that 1800 MHz RF radiation could cause oxidative damage to mtDNA in primary cultured neurons. Oxidative damage to mtDNA may account for the neurotoxicity of RF radiation in the brain. It is safe to conclude from a reading of the totality of studies relating EMF to cancer, to which I have accessed so far, that EMF is a highly probable cancer hazard contributing worldwide to significantly increased human and non-human morbidity and mortality. While it may be more statistically formal to do a Meta-Analysis on the studies (Mann, C. 1990. Meta-Analysis in the Breech. Science (249):476-480.), the trends are so strong that I doubt that any significant change in the final interpretation would result. DAMAGE TO MITOCHONDRIAL DNA WOULD ALSO BE COMPOUNDED WITH COVID ATTACK ON MITOCHONDRIA ALSO DAMAGING THE DNA AND EVEN POSSIBLY RUPTURING THE MITOCHONDRIA. THIS WOULD CREATE A DOUBLE HIT ON THIS VITAL ORGANELLE. ANTIBIOTICS ADMINISTERED TO PATIENTS DURING TREATMENT CAN ALSO DAMAGE THE MITOCHONDRIA. THIS SORT OF DAMAGE IS LINKED TO HEART DISEASE AND CANCER (J. JYRKKANEN AUG 2021).

Existentially Critical Climate and Environment Policy Issues Needing Immediate attention to Ward off Extinction. Two Videos. 2022-11-11. Jorma Jyrkkanen

ARE WE NEARING THE FATE OF THE DINOSAURS WITH FOSSIL FUEL LEADING THE ACCELERATOR?

TO VIEW MY CLIMATE SCIENCE SITUATION REPORT VIDEO AND THE CANADIAN ENVIRONMENT POLICY VIDEO GOOGLE Jormawankenobe and open Playlist TOXICOLOGY.

Free Trade is Fraud. There is Nothing Free About the Carbon Cost Dumped on the Atmosphere. 2022-1-30. Jorma Antero Jyrkkanen

Is Trade Free? Not in any aspect. Every movement of goods anywhere in the world has an environmental cost due to the energy consumed. That energy is used in making the infrastructure of trade, the transportation equipment, spent in the delivery and distribution.

932 MILLION TONNES(1000 KGS)=932 BILLION KGS CO2 IS PROOF FREE TRADE IS DEADLY GREENWASHING FRAUD. TO THESE EMISSIONS ONE HAS TO ADD THE GREENHOUSE GAS COST OF SMELTING THE STEEL AND ALUMINUM FOR SHIPS AND CONTAINERS AND THE ENERGY USED IN WELDING THEM TOGETHER. CLIMATE BUSTING UNFREETRADE.

Evolution is the Creator. GENERAL THEORY OF UNIVERSAL EVOLUTION. 5 April 2012 Jorma Antero Jyrkkanen, BSC, PDP

My observation that our quarks, gluons and electrons are ancient universe assembled by Physical and Organic evolution into a primate that is now pondering itself, the Parent Universe and Evolution as the Creator is the material foundation for the dawning of a new age of philosophical-scientific-spiritual enlightenment that allows us to be proud and noble in our discovered connection to the our mother universe. We fabricated in far off times imaginary mythical Creator Gods (https://www.godchecker.com/) many in our own image during our pre-scientific genesis. This is I think my most important conclusion. We are the universe. We are the mind of the universe pondering and speaking about itself and have even created a new quasi universe, cyberspace. We are ephemeral and transient and will go extinct one day and return to our quarks, gluons and electrons.

General Theory of Universal Evolution by Jorma Jyrkkanen GENERAL THEORY OF UNIVERSAL EVOLUTION 5 April 2012 My Theory was Presented at the April 12 2012 meeting of The Central Okanagan Naturalists Club to a full house as The Evolution Bit Darwin Couldn't Possibly Know, from Higgs to Comparative Genomics. More has emerged recently on the role of chance and epigenetics. http://www.okanagannature.org/ Thank you ladies and gentlemen for this opportunity to share my limited understanding of this vast subject with you. There are insights here for philosophy, human relations and our relationship with all life and even our place in the universe. A different paradigm emerges from these considerations than the one we have inherited through cultural evolution born in ignorance and mythology. I am humbled by the enormity of it all. PHYSICAL EVOLUTION, THE CREATION OF THE FRAMEWORK FOR ORGANIC EVOLUTION

Big Bang-release of eternal energy, expansion, cooling, 4 Forces peeled off. The laws of the universe emerge with pure energy from the singularity. -Higgs energy field, is everywhere, imparts mass to particles. I like to think of bottom spin on a cue ball stuttering on a rutted table top made of energy density which raises energy of the ball, entangling it with space time which translates into mass. Excitation of the Higgs field is the Higgs Boson. M Theory says strings moving through 11 dimensions causes mass. Einstein E=mc^2 -Since the energy density is the fabric of space time I imagine quantum mechanics is entangled with space time through the Higgs interaction creating the phenomenon Einstein called relativity and which I conjecture imaginatively as gravitational entanglement, the conjugation of quantum mechanics and relativity. -Standard model, quantum mechanics, quantum entanglement and gravity, relativity. It is all about the behavior of energy and how it gathers and interacts. -The DNA of the physical universe is the shape-set of the curled invisible dimensions of string theory. Each shape-set determines the properties of a possible universe. There are 10^500 possible shapes. (I owe this idea to my online Physics Professor, Dr. Leonard Susskind Felix Bloch Professor of Physics, Princeton) -Quark gluon gamma ray soup. The Big Bang diversion via expansion, cooling, layers of the four forces diverge. -Protons and anti-protons form -Symmetry splitting, more protons than antiprotons->proton (matter) universe. They p differ in half lives enabling matter to dominate. Quarks gather in protons and neutrons. Creation of atomic nuclei. -Gases cool, gravity collects into early galaxies and suns. Convergence. -Galaxies, suns, supernovas are born leading to fusion, fission, beta decay nucleosynthesis of elements, periodic table is filled. Our building ingredients mfg'd (O, C, N, S, Fe, Ca, Mg, Na, K, ...) ie created. Creation of new atomic species from gathering protons and neutrons into atoms by electron shells (SPDF orbitals). -Supernovas blow elements into surrounding universe in another Big Bang divergence, expansion carries them off into foamy matrix, gravity collects ejecta into solar systems, planets in another convergence inside galaxies. Supernovas happen every day. Periodic table elements being re-created universe wide constantly. NUCLEOSYNTHESIS OF ATOMS

-Quantum mechanics creates molecules for life both in space and on earth and in space, ex. AA, nucleic acids, ribose. Varieties exist just like with Darwin's finches. -Asteroids, comets deliver molecules of life to planets and some are created by Urey Miller synthesis. In Goldilocks planets there is biomolecular synthesis of AA, proteins, nucleic acids; ongoing also in other regions of the universe in various stages. Combinants converge. Super varieties formed. -Physical evolution creates materials and opportunity for infinite chance events to diversify and a framework for them to happen and exist within. Given infinite time and space and randomness, the least improbable event becomes certitude. -Physical evolution is the creator of the universe and science is the way to know it. We are inseparably part of it all and the energy in our quarks and electrons is as ancient as the big bang, 13.7 bya. -The universe is homogenous enough to assert definitively that these physical evolutionary synthetic processes are broadly similar and universe wide such as to set the stage for organic evolution throughout the cosmos with vagaries of serendipity helping dictate the exact results whence cometh my assertion of the General Theory. Supernovae function vis a vis nucleosynthesis and cooling related force delamination phase changes are likely not affected by modest changes in homogeneity nor isotropy even in an accelerating universe. We are quarks, gluons, electrons and pure energy at root. We are a microcosm of the universe assembled from itself by physica evolution and organic evolution. Physical evolution is the creator of the universe and sets the stage for the evolution of life if chance permits and it does.

ORGANIC EVOLUTION; THE BIOSYNTHESIS OF MOLECULES OF LIFE AND LIFE ITSELF -Urey-Miller biomolecular synthesis, CH4, NH3, H2, H2O, (HCN) -life starts, Pr-Lipid, RNA-Pr lipid, DNA-RNA-Protein, -Watson Crick DNA RNA elucidation as the genetic code of life on earth

ONE THEORY OF ORIGINS Abstract How and where did life on Earth originate? To date, various environments have been proposed as plausible sites for the origin of life. However, discussions have focused on a limited stage of chemical evolution, or emergence of a specific chemical function of proto-biological systems. It remains unclear what geochemical situations could drive all the stages of chemical evolution, ranging from condensation of simple inorganic compounds to the emergence of self-sustaining systems that were evolvable into modern biological ones. In this review, we summarize reported experimental and theoretical findings for prebiotic chemistry relevant to this topic, including availability of biologically essential elements (N and P) on the Hadean Earth, abiotic synthesis of life's building blocks (amino acids, peptides, ribose, nucleobases, fatty acids, nucleotides, and oligonucleotides), their polymerizations to bio-macromolecules (peptides and oligonucleotides), and emergence of biological functions of replication and compartmentalization. It is indicated from the overviews that completion of the chemical evolution requires at least eight reaction conditions of (1) reductive gas phase, (2) alkaline pH, (3) freezing temperature, (4) fresh water, (5) dry/dry-wet cycle, (6) coupling with high energy reactions, (7) heating-cooling cycle in water, and (8) extraterrestrial input of life's building blocks and reactive nutrients. The necessity of these mutually exclusive conditions clearly indicates that life's origin did not occur at a single setting; rather, it required highly diverse and dynamic environments that were connected with each other to allow intra-transportation of reaction products and reactants through fluid circulation. Future experimental research that mimics the conditions of the proposed model are expected to provide further constraints on the processes and mechanisms for the origin of life. This line of work posits the criticality of cyanide, alpha keto acids, ammonia and carbon dioxide.

Research Paper. Origins of building blocks of life: A review; Author NorioKitadai, ShigenoriMaruyama Prior thinking was insprired by the Urey Miller Experiments utilizing methane, hydrogen, water vapour and carbon dioxide and aldehydes. Nucleotides can be created from fairly simple ingredients. -Molecular genetics determines all life has RNA or DNA and RNA and Proteins -Venter and Colleagues elucidate human genome and many many more proving the DNA/RNA based genetic code programs all like on earth and common ancestral origins for all life. -Codification in DNA proves relatedness, degree of similarity in DNA sequence, function relates to degree of relatedness -bacteria earliest life forms (side effect that bacteria feel right at home in us/on us). -bacteria evolved photosynthetic pigments -early bacteria evolved glycolysis ie energy fm sugars -mitochondria bacters (Rickettsias, SAR II) evolved metabolism of pyruvate via citric acid cycle. 36 ATP vs 2 ATP without mitochondria. Mutations in mitochondrial DNA cause myopathies. What we got from our primal bacteria cell merging with mitchondria was energy for work. Primal cell may have also been a ciliate as suggested by oour lung cilia and sperm tails which are near identical to Eukaryote cilia in electron microgrpah cross section. Mitochondrial Endosymbiosis probably with an Archaea cell producing the 3 branches of higher life.

-metazoa evolved by endosymbiosis of p amoeboid cells and mitochondria (SAR II, Ricketsia bacterai) and these evolved into higher animals forms, Protista, Invertebrata, via mergers and acquisitions and lateral transfers, ongoing. -plants evolved by a primal cell merging with endosymbiont mitochondria bacteria and chloroplast bacteria -higher early animals evolved p by Garstang hypothesis process inverts to verts; protogeny of Ascidians, where larva became an adult -Chordates to Vertebrates cephalization with mouth and sensory organs in the front end, gills, jaws, bilateral symmetry, post anal tail, segmented myomeres, cartilagenous notochord, dorsal hollow neural tube, coelom, egenes -Fish (Crossopterigia) evolvedctoderm, mesoderm, endoderm, tissue development by HOX fins into feet and lungs (Dipnoi, lung fish) for gulping air colonizing land as Amphibia -Some Amphibia evolved the amniotic egg that was able to withstand drying conditions forming reptilia and Synapsids which later formed Therapsids and later Mammals and us. A very ancient one found to date was The Hylonomus lyelli, 312 million years old and was discovered in a petrified tree stump near Joggins in the Bay of Fundy, 250 kilometres north of Halifax. The fossil was uncovered by Nova Scotian geologist John William Dawson in 1859 but was handed over to the British Museum around the turn of the century.Apr 24, 2011. Evolution of Amniotes The first amniotes evolved from their amphibian ancestors approximately 340 million years ago during the Carboniferous period. The Amniote Egg.

This is a stem amniote, Protoclepsydrops. Chances are good we once looked like this for a considerable length of time. Looks a tad like Pederpes from the Romer's Gap.

The early amniotes diverged into two main lines soon after the first amniotes arose. The initial split was into synapsids and sauropsids. Synapsids include all mammals, including extinct mammalian species. Synapsids also include therapsids, which were mammal-like reptiles from which mammals evolved. The middle one below is our synapsid ancestor skull form.

-Reptilia ruled til the big asteroid 66.046 million years ago which gave opportunities to mammals. They (Ex Morganuccodon) gave rise to ears, large brains, complex behaviour in mammals w hair, placenta, live immature young, warm blooded, milk and birds. A stem Eutherian (true mammals-our group) Juramia.

Juramaia Skeleton and note dentition had evolved diversity.

- Tree shrew types survived the asteroid to become loris, lemurs, tarsiers, monkeys. Gliding Tree Lemurs as exemplified by the the Colugo are the extant living ancestors of the Primates, our line.

-Those evolved into primates which evolved into us bags of up/down quarks held together w gluons wrapped in whizzy electrons. We invented the Gods to explain how and why but then discovered science, the new how and why. We ponder Higgs, the Genetic code of all life and evolutionary creation.

-Darwin showed surplus production, variants, competition, nature selects, fittest survive. We have since learned about the role of luck. It matters.Primate Evolution produced considerable diversity.

-Venter made a synthetic organism come to life. He picked DNA he wanted, put them together and stuck em in an empty yeast capsule and it worked, did what he wanted. -Geneticists showed populations of genes carried traits and these are acquired from ancestors via linear transfer and also form lateral transfer ex HERV's, bacterial DNA -All living things are kin if you go back far enough. The triplet code for amino acids is constant in all life and this is the strongest evidence all life had a common ancestor and we are all kin, yes evry living thing is kin to us.

-We are a composite of a lot of lateral gene insertions, duplications, mutations, deletions, mergers and and linear injections, a chimaera if you will. All living things are composites. Each merger gave us a set of traits that we have for genetic baggage with fit ones being fixed, bad ones stored, altered or deleted. We are a committee of genomes and genes. -Science is about the creation and the creation process and we could properly call it creation science. -Life begins at the subatomic level when assemblages of quarks begin to cannibalize other assemblages to extract energy and replacement parts. It ceases when the cannibalization stops. SUMMARY OF PHYSICAL AND ORGANIC EVOLUTION INTO THE GENERAL THEORY OF UNIVERSAL EVOLUTION The energy in our atoms is of infinite age and p has always existed by energy conservation laws and needed no creator. Our mother and father were the big bang, supernovas and suns acted upon by gravity, molecular synthesis induced by quantum mechanical effects acting with the four forces, and earth, dashed by asteroids and comets carrying life's molecules, and the organic soup on earth, fired by lightening and fires. A homogenous isotropic universe would have the conditions for life being constantly created by supernovas dispersed approximately as we see spiral galaxies dispersed. this may not be true at boundary conditions. There is an acceleration towards a preferred region of space suggesting periferal anisotropy. The same atoms that are associated with life, and physical processes like nucleosynthesis and quantum mechanics are everywhere in the universe suggesting myriads of opportunities for life elsewhere. Given infinite time and random rolls of the dice the most improbable event becomes certitude. We are a bag of quarks surrounded by electrons causing tiny dimples in space time which in turn gives us our mass through gravity. We spend most of eternity in the atomic and molecular states which only move according to Newton's Laws and a tiny fraction in a virtual mobile form. We can be completely boiled down into three bags, on with up quarks, another with down quarks, a bottle of gluon and a bag of electrons. We are both infinitely old energy, 13+ byo quarks and electrons, atoms of star stuff, created by physical and organic evolution into the mind of the universe, now pondering the universe and our creator, universal evolution. We humans made the thousands of Gods to explain all this before science. All living things are family. The universe is our home and womb, Earth is our heaven. Energy is eternal. All the laws of physics were contained in the singularity. Was it intelligent and benevolent? it was pregnant with possiblity and thats one thing we can count on. Evolution is pretty cruel from time to time and flawed so its hardly benevolent. So what are humans and why are we here? I call this the cypher. The how is the why and science explains how and this tells us why things are what they are. To know why, find out how. It answers an enoromous philosophical void. https://humanorigins.si.edu/education/introduction-human-evolution WHAT THEN ARE WE HUMANS? 1 March 2012 The energy in our atoms is of infinite age and p has always existed by energy conservation laws and needed no creator. Our mother and father were the big bang, supernovas and suns acted upon by gravity, molecular synthesis induced by quantum mechanical effects acting with the four forces, and earth, dashed by asteroids and comets carrying life's molecules, and the organic soup on earth, fired by lightening and fires. A homogenous isotropic universe would have the conditions for life being constantly created by supernovas dispersed approximately as we see spiral galaxies dispersed. this may not be true at boundary conditions. There is an acceleration towards a preferred region of space suggesting periferal anisotropy. The same atoms that are associated with life, and physical processes like nucleosynthesis and quantum mechanics are everywhere in the universe suggesting myriads of opportunities for life elsewhere. Given infinite time and random rolls of the dice the most improbable event becomes certitude. We are a bag of quarks surrounded by electrons causing tiny dimples in space time which in turn gives us our mass through gravity. We spend most of eternity in the atomic and molecular states which only move according to Newton's Laws and a tiny fraction in a virtual mobile form. We are both infinitely old energy, 13+ byo quarks and electrons, atoms of star stuff, created by physical and organic evolution into the mind of the universe, now pondering the universe and our creator, universal evolution. All living things are family. The universe is our home and womb, Earth is our heaven. Energy is eternal. All the laws of physics were contained in the singularity. Its likely chance alone enabled life in our universe? it was pregnant with possiblity and thats one thing we can count on. Evolution is pretty cruel from time to time and flawed so its hardly benevolent or intelligent. It just works like a hot dam. Physical and organic evolution, universal evolution, are the creator, governed by the laws of nature. We are e the universe become conscious pondering itself. We are the mind of the universe in very real sense. We made stories in mythology and the gods to explain the how and why and now science teaches us how the laws of nature made everything from energy. I dedicate this Theory to my Late Brother Dougy Jyrkkanen wo died in a tragic accident as a Youth. We discussed investigation of this topic when paddling down the Skagit River in a raft while doing phenology and deer studies for Slaney while I was a Zoology student at UBC.

Copyright 2012 Jorma Jyrkkanen. All rights reserved. Tags: Evolution, physical evolution, organic evolution, General Theory of Universal Evolution, Jorma Jyrkkanen

Antibiotics Discussion. Risks and Benefits. Mitochondrial Poisons? Discussion by Suárez-Rivero JM, Pastor-Maldonado CJ, et al. 2022-10-25. Jorma Jyrkkanen

The discovery and application of antibiotics in the common clinical practice has undeniably been one of the major medical advances in our times. Their use meant a drastic drop in infectious diseases-related mortality and contributed to prolonging human life expectancy worldwide. Nevertheless, antibiotics are considered by many a double-edged sword. Their extensive use in the past few years has given rise to a global problem: antibiotic resistance. This factor and the increasing evidence that a wide range of antibiotics can damage mammalian mitochondria, have driven a significant sector of the medical and scientific communities to advise against the use of antibiotics for purposes other to treating severe infections. Notwithstanding, a notorious number of recent studies support the use of these drugs to treat very diverse conditions, ranging from cancer to neurodegenerative or mitochondrial diseases. In this context, there is great controversy on whether the risks associated to antibiotics outweigh their promising beneficial features. The aim of this review is to provide insight in the topic, purpose for which the most relevant findings regarding antibiotic therapies have been discussed.

Suárez-Rivero JM, Pastor-Maldonado CJ, Povea-Cabello S, Álvarez-Córdoba M, Villalón-García I, Talaverón-Rey M, Suárez-Carrillo A, Munuera-Cabeza M, Sánchez-Alcázar JA. Mitochondria and Antibiotics: For Good or for Evil? Biomolecules. 2021 Jul 17;11(7):1050. doi: 10.3390/biom11071050. PMID: 34356674; PMCID: PMC8301944.

Jobs recommended to me from ResearchGate.org. 2022-10-22. Jorma yrkkanen

CAN WE BOOST MITOCHONDRIAL NUMBER IN A WAY CONSISTENT WITH ORIGINAL CELLULAR TISSUE TYPE FUNCTION? THOUGHTS. 2022-10-21

IS IT POSSIBLE TO REPLACE DAMAGED MITOCHONDRIA PHARMACOLOGICALLY?

Jornayvaz FR, Shulman GI. Regulation of mitochondrial biogenesis. Essays Biochem. 2010;47:69-84. doi: 10.1042/bse0470069. PMID: 20533901; PMCID: PMC3883043. CAN WE FACILITATE MITOGENESIS BY PROTEIN DEFICIENT FASTING? CAN WE INTRODUCE OR BOOST AMPK PRODUCTION TO STIMULATE MITOGENESIS NUMBERS CONSISTENT WITH CELL DEFICIENCY AND TISSUE SPECIFIC REQUIREMENTS? CAN WE PHARMACOLOGICALLY BOOST MITOGENESIS TO PROVIDE FOR LOSSES TO ANTIBIOTICS, PESTICIDES AND COVID AND OTHER BIOCIDES? iT OCCURS TO ME WE ARE ONLY AS OLD AS OUR MITOCHONDRIA?